Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEVFDMSQVITDKTFNEETDK--GLVLIDFWATWCGPCRMQAPILDQLEQEYDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQYL 2H6X Chain:A ((7-107)) ---------LTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILDEIADEY-QGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKEFLDANL

General information: TITO was launched using: RESULT: Template: 2H6X.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 409 17105 41.82 172.78 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.82 3D Compatibility (PKB) : 41.82 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.82 QMean score : 0.539

(partial model without unconserved sides chains): PDB file : Tito_2H6X.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2H6X-query.scw PDB file : Tito_Scwrl_2H6X.pdb: