Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYNSAMKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVCLITTKRALKPEPHPNLSIREVTNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGLEEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLV---KEWNPTIHLIGFKLLVDVTEDHLVDIARKSLIKNQADLIIANDLTQ----ISADQH--RAIFVEKNQLQTVQTKEEIAELLLEKIQAYHS 1U7Z Chain:A ((9-216)) -----LNIMITAGPTREPLDPVRYISDHSSGKMGFAIAAAAARRGANVTLVSGPVSL-PTP-PFVKRVDVMTALEMEAAVNASVQQQNIFIGCAAVADY-----------RAATVAPEKI------------DELTIKMV-KNPDIVAGVAALKDHRP--YVVGFAAETNNVEEY----ARQKRIRKNLDLICANDVSQPTQGFNSDNNALHLFWQDGDKVLPLERKELLGQLLLDEI-----

General information: TITO was launched using: RESULT: Template: 1U7Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1035 -58567 -56.59 -305.04 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : -56.59 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.408

(partial model without unconserved sides chains): PDB file : Tito_1U7Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1U7Z-query.scw PDB file : Tito_Scwrl_1U7Z.pdb: