Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRSLLSEMLNQVSDLDADEVAELLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEND--WALPGGFGEVGYSPTENILKEIEEETGFKAKVERLLAVFD--TNRFQLQSKQYAKFVFECKLLDGQFQENQEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD 3O8S Chain:A ((68-191)) ------------------------------------------------------------------TPKLDTRAAIFQEDKILLVQ---ENDGLWSLPGGWCDVDQSVKDNVVKEVKEEAGLDVEAQRVVAILDKHKNNP-----RVTKVFILCRLLGGEFQPNSETVASGFFSLDDLPPLYLGKNTAEQLAL--------------

General information: TITO was launched using: RESULT: Template: 3O8S.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 544 14053 25.83 122.20 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : 25.83 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.462

(partial model without unconserved sides chains): PDB file : Tito_3O8S.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3O8S-query.scw PDB file : Tito_Scwrl_3O8S.pdb: