Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSLKTELVIFDWDGTLYNSVGQIVASLQHAAEEHKLTLTDEAAKSIIGLGLPEVMQTLFPEVPDLHDSI----LKAYGDHYIANST-NDAWFEGISELLHDLKAQGLKLAVATGKNRRGLDRVIAKTQSTHLFDVTRAAN---ETRSKPDPLMLQEILTVTGVSVEQAVMIGDSSYDLEMAQRLGMPRIGVGYGVHSVEVLQQFQPLTIAKDVSELHNFLREYAKLSTVDVA 3MC1 Chain:A ((7-211)) -------VLFDLDGTLTDSAEGITKSVKYSLNKFDIQVEDLSSLNKF-VGPP--LKTSFMEYYNFDEETATVAIDYYRDYFKAKGMFENKVYDGIEALLSSLKDYGFHLVVATSKPTVFSKQILEHFKLAFYFDAIVGSSLDGKLSTKED--VIRYAMESLNIKSDDAIMIGDREYDVIGALKNNLPSIGVTYGFGSYEELKNAGANYIVNSVDELH---------------

General information: TITO was launched using: RESULT: Template: 3MC1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1075 3983 3.71 20.22 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : 3.71 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.494

(partial model without unconserved sides chains): PDB file : Tito_3MC1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3MC1-query.scw PDB file : Tito_Scwrl_3MC1.pdb: