Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNTDTALIMALPNESKGLFEQAGIEVHYSGIGKINAAFKAFEVIQKTGCKTLINLGTAGS--SSFNRHDLVEIKTFVQRDMDVSPLGFEVG-VTPLDDHLAAEIHLQT----HFADLP-----KGICGTGDSF----ETGQ------PKVACDVVDMEGYALAKVCHKLGVRLISVKYITDGADDTAHLDWEENLLLGAQKLLALYQNHF 3DP9 Chain:A ((48-222)) ----------------------------SGIGKVSAALGTALLISQYAPDVVINTGSAGGFDASLNVGDVVISSEVRHHDADVTAFGYEIGQMAGQPAAFKADEKLMTVAEQALAQLPNTHAVRGLICTGDAFVCTAERQQFIRQHFPSVVA--VEMEASAIAQTCHQFKVPFVVVRAISDVADKESPLSFEEFLPLAAKSSSAM-----

General information: TITO was launched using: RESULT: Template: 3DP9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 784 13972 17.82 91.32 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : 17.82 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.484

(partial model without unconserved sides chains): PDB file : Tito_3DP9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3DP9-query.scw PDB file : Tito_Scwrl_3DP9.pdb: