Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYEPYPVPEQVREQKLSRYSSLWTFAKQDLRLLLFFLIIAGLVGLGIGYFWSCIFIAFVVFFTLQLRSLYLVNDWIANNPYDVPPNLNGIWGALLFNVYRAQRQERIVQAEMVGLIDRAQSSLVALAEAVVLIDDQHQIEWWNPAAERLLGISPLDRGRNLLTILRQPTFIEYFNNIDQAPDGIKLHSNLDDDRYVQVKLTRFGGESRLLVAYDVTRMHNLEQMRKDFVDNISHELRTPLTVLSGYIETFTDQEDINPRWKRAFDQM-QSQTKRMNALVNDLLLLSNLENNKKIAKNQIIEMPSLMNQLFDD-----AQAYNADYGHTLNLHIDSHCDLIGSDME-IASAFSNLITNAIKYTPKGGTITIGWHDDGEHAYFSVQDTGIGINPKHLPRLTERFYRVDSDRSRQTGGTGLGLAIVKHVLMQQGAYLDVQSKENEGSTFTAVFPKERLYNMT 4ZKI Chain:A ((25-263)) ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VTEQQKIDNDRKQFVSNVSHELRTPLTSLRSYIEALSDGAWKDPEVAPGFLKVTQEETDRMIRMINELLSLSRMDSGTTRVDMELVNINEMFNYVLDRFDMILKKD-NPAKYYTIKREFTKRDLWVEIDTDKFTQVLDNIMNNAIKYSPDGGVVTCRLLETHNQVIISISDQGLGIPRADLGHVFDRFFRVDK-----QGGTGLGLAISKEVVQMLGGRIWVDSVEGKGSTFYISLPYE------

General information: TITO was launched using: RESULT: Template: 4ZKI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 822 11978 14.57 53.00 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : 14.57 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.444

(partial model without unconserved sides chains): PDB file : Tito_4ZKI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4ZKI-query.scw PDB file : Tito_Scwrl_4ZKI.pdb: