Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLLTVIYIIAITAEAMTGALSAGRRSMDWFGVVLIACVTALGGGSVRDVLLGHYPLTWVKHPEYLVLTCCAAFVTIVIAKWMR--HLHNIFLVLDALGLIGFTIIGCQIALQMGHGFVVSAVAGVLTGVSGGILRDILCNDVPFVFRRELYASISFVAVICYWVCLDLGLSLELTVISTLVFGFTLRLIAIYFGLEMPKFIYKDDDAESASSTDEH 5WTR Chain:A ((3-197)) MILELLNIIGIIAFTISGSLKGTNKGLDIFGVVTLGVITSYAGGIIADILLGIYPPQILKELNYLLLSVGISIFVFYFYKWLQTNPIKMIIAISDAVGLSTFATLGASLAYSYGLNPISVGLIAAIVGTGGGVIRDVLVNEIPMVLTKEIYATAALLSGFIYYFTTPYLHHDSLFV--AFLGSFLLRILSIKYNFNL-------------------

General information: TITO was launched using: RESULT: Template: 5WTR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 994 -187139 -188.27 -969.63 target 2D structure prediction score : 0.73 Monomeric hydrophicity matching model chain A : 0.82 3D Compatibility (PKB) : -188.27 2D Compatibility (Sec. Struct. Predict.) : 0.73 1D Compatibility (Hydrophobicity) : 0.82 QMean score : 0.390

(partial model without unconserved sides chains): PDB file : Tito_5WTR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5WTR-query.scw PDB file : Tito_Scwrl_5WTR.pdb: