Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGHSVALNFADGKTFFISVNKDELLLDAAVRQGINLPLDCREGVCGTCQGQCETGIYEQEYVDEDALSERDLAERKMLACQTRVKSDAAFYFDHDSAICNAGDTLKIETQVTAVELVSETTAILHLD-ASNHAEQLQFLPGQYARLQIPDTE--------------DW-----------------RSYSFANRPNATNQLQFLIRL---------LPDGVMSNYLRDRCQVGQSLLIEAPLGSFYLREVERPLVFVAGGTGLSAFLG-MLDNLVEQPNSPTVQFYYGVNSETDLCEQQRLHAYAEQLPNFSYHPIVT--KATETWQGKAGYIH----EHLNKDQLAEQAFDMYLCGPPPMIEAVKNWLDEQALQNYRIYSEKFLQSNTSR 4P6V Chain:F ((96-406)) ----------------------------------------------------------------DHISKGEAREGERLACQVAVKADMDLELPEEIFGVK-------KWECTVISNDNKATFIKELKLAIPDGESVPFRAGGYIQIEAPAHHVKYADFDVPEKYRGDWDKFNLFRYESKVDEPIIRAYSMANYPEEFGIIMLNVRIATPPPNNPNVPPGQMSSYIWS-LKAGDKCTISGPFGEFFAKDTDAEMVFIGGGAGMAPMRSHIFDQLKRLKSKRKMSYWYGARSKREMFYVEDFDGLAAENDNFVWHCALSDPQPEDNWTGYTGFIHNVLYENYLKDHEAPEDCEYYMCGPPMMNAAVINMLKNLGVEEENILLDDF-------

General information: TITO was launched using: RESULT: Template: 4P6V.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain F - contact count / total energy / energy per contact / energy per residue : 1203 10656 8.86 40.52 target 2D structure prediction score : 0.47 Monomeric hydrophicity matching model chain F : 0.70 3D Compatibility (PKB) : 8.86 2D Compatibility (Sec. Struct. Predict.) : 0.47 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.388

(partial model without unconserved sides chains): PDB file : Tito_4P6V.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4P6V-query.scw PDB file : Tito_Scwrl_4P6V.pdb: