Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPAVKSNRPVNLSMGQVLAVNLRSPV-AIASILHRLSGVIVFLLVPVLLWILDKSLSSPEGFDYVKNVVFGNILVRFVVWVFVAGLIFHFIAGVKHLLADLGFAEE-LQSGRIAATISLILSVVAIIAAFVWIVF 2WDQ Chain:C ((8-119)) ------QRPVNLDLQ-----TIRFPITAIASILHRVSGVITFVAVGILLWLLGTSLSSPEGFEQA-SAIMGSFFVKFIMWGILTALAYHVVVGIRHMMMDFGYLEETFEAGKRSAKISFVITVV-----------

General information: TITO was launched using: RESULT: Template: 2WDQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 229 -38689 -168.95 -351.71 target 2D structure prediction score : 0.75 Monomeric hydrophicity matching model chain C : 0.79 3D Compatibility (PKB) : -168.95 2D Compatibility (Sec. Struct. Predict.) : 0.75 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.187

(partial model without unconserved sides chains): PDB file : Tito_2WDQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2WDQ-query.scw PDB file : Tito_Scwrl_2WDQ.pdb: