Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSHGMAGLPTATLIGQVELGRQVSIWFGAVVRADNCVVRIGNFSNIQENSVLHTDAGLELNIGEYVTVGHKVMLHGCTIGDNSLIGMNAVILNRAVIGKNCIIGANALIPEGKVIPDNSVVMGSPGKIVKTLDEEGAAKIRLSALHYAEHFKSYADLKEFYF 1V67 Chain:A ((23-161)) ----------AVVIGDVVLEEKTSVWPSAVLRGDIEQIYVGKYSNVQDNVSIHTSHGYPTEIGEYVTIGHNAMVHGAKVGNYVIIGISSVILDGAKIGDHVIIGAGAVVPPNKEIPDYSLVLGVPGKVVRQLTEEEIEWTKKNAEIYVE-------------

General information: TITO was launched using: RESULT: Template: 1V67.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 854 -126004 -147.55 -906.50 target 2D structure prediction score : 0.47 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -147.55 2D Compatibility (Sec. Struct. Predict.) : 0.47 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.490

(partial model without unconserved sides chains): PDB file : Tito_1V67.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1V67-query.scw PDB file : Tito_Scwrl_1V67.pdb: