Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYLTL--PGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKG-LPGTTPSYYFVIDPDGYKIEVIRG 5D7Z Chain:A ((24-147)) -RMLHAVYRVGDLDRTIKYYTECFGMKLLRKRDVPDEKYTNAFLGFGPENTNFAVELTYNYGVDKYDIGTGFGHFAIANDDVYKLAENIKSKGGKITREPGPVKGGSTVIAFAQDPDGYMFELIQ-

General information: TITO was launched using: RESULT: Template: 5D7Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 504 -10280 -20.40 -84.95 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain A : 0.82 3D Compatibility (PKB) : -20.40 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.82 QMean score : 0.637

(partial model without unconserved sides chains): PDB file : Tito_5D7Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5D7Z-query.scw PDB file : Tito_Scwrl_5D7Z.pdb: