Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence AILGFVNKQQAHDLLINKPDGTFLLRFSDSEIGGITIAWKL----DSPERNLWNLKPFTTRDFSIRSLADRLGDLSYLIYVF 5D39 Chain:A ((419-493)) -IIGFISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDGSPQ--IENIQPFSAKDLSIRSLGDRIRDLAQL----

General information: TITO was launched using: RESULT: Template: 5D39.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 232 -13459 -58.01 -189.56 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.84 3D Compatibility (PKB) : -58.01 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.84 QMean score : 0.606

(partial model without unconserved sides chains): PDB file : Tito_5D39.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5D39-query.scw PDB file : Tito_Scwrl_5D39.pdb: