Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIRGFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSS-YPLYITTTKNTSTAQDMAKNLEIHHFFDGIYGS---SPEAPHKADVIHQALQTHQLVPQQAIIIGDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQ-PDYIAHKPLEVLAYFQ 2NYV Chain:A ((2-201)) --SLRVILFDLDGTLIDSAKDIALALEKTLKELGLEEYYPDNVTKYIGGGVRALLEKVLKDKFREEYVEVFRKHYLENPVVYTKPYPEIPYTLEALKSKGFKLAVVSNKLEELSKKILDILNLSGYFDLIVGGDTFGEKKPSPTPVL-KTLEILGEEPEKALIVGDTDADIEAGKRAGTKTALALWGYVK----LNSQIPDFTLSRP--------

General information: TITO was launched using: RESULT: Template: 2NYV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1022 -44743 -43.78 -229.45 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : -43.78 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.492

(partial model without unconserved sides chains): PDB file : Tito_2NYV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2NYV-query.scw PDB file : Tito_Scwrl_2NYV.pdb: