Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTVLEAY-QIVSSIHRRNS-LTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQAL-RNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLAILCNYANNLANTPINPELQPYA 3C1L Chain:A ((32-172)) ----------------------------GLVPNVLKAYAFDDKKLRAFTDIYNDLMLGESGLSKLDREMIAVAVSSINHCYYCLTAHGA-AVRQLSGDPALGEMLVMNFRAADLSPRQTAMLEFAVKLTEEPAKIVEADRAALRKAGFSDRDIWDI---ASTAAFFNMSNRVA------------

General information: TITO was launched using: RESULT: Template: 3C1L.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 536 -20236 -37.75 -146.63 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -37.75 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.452

(partial model without unconserved sides chains): PDB file : Tito_3C1L.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3C1L-query.scw PDB file : Tito_Scwrl_3C1L.pdb: