Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPTILITGASGGLAQEMVKLLPND--QLILLGRNKEKLAQLYGNYSHAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEVNTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRLELMPYGVYVTTVNPGPIRTGFF----DQADPDGTYLKSVDR-FLLEPDAVAKKIVKIIGKNKRELNLPILLNLAHKFYTLFPKLADKLAGETFNYK 3P19 Chain:A ((19-230)) ---VVITGASSGIGEAIARRFSEEGHPLLLLARRVERLKAL--NLPNTLCAQVDVTDKYTFDTAITRAEKIYGPADAIVNNAGMMLLGQIDTQEANEWQRMFDVNVLGLLNGMQAVLAPMKARNCGTIINISSIAGKKTFPDHAAYCGTKFAVHAISENVREEVAASNVRVMTIAPSAVKTELLSHTTSQQIKDGYDAWRVDMGGVLAADDVARAVL-----------------------------------------

General information: TITO was launched using: RESULT: Template: 3P19.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1029 -22451 -21.82 -109.52 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -21.82 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.469

(partial model without unconserved sides chains): PDB file : Tito_3P19.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3P19-query.scw PDB file : Tito_Scwrl_3P19.pdb: