Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVAAQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFLTHAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPYL-YNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLDGKHPVFGQVIGGMDVVDKIAKAEKDEKD-KPTTAITIDSIEVVKDYDFKS 2OJU Chain:A ((9-160)) ---------------------------------------------------------------------------VTLHTDVGDIKIEVFCERTPKTCENFLALCASNYYNGCIFHRNIKGFMVQTGDPTGTGRGGNSIW---------GKKFEDEYSEYLKHNVRGVVSMANNG-PNTNGSQFFITY------------------------GKQPHLDMKYTVFGKVIDGLETLDELEKLPVNEKTYRPLNDVHIKDITI--------

General information: TITO was launched using: RESULT: Template: 2OJU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 750 -22536 -30.05 -150.24 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -30.05 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.640

(partial model without unconserved sides chains): PDB file : Tito_2OJU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2OJU-query.scw PDB file : Tito_Scwrl_2OJU.pdb: