Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGLFTLKEVSHYLIENKNMAWSITMCLVAVLLTIFILNLILGLLVHFFDYSEPIWWHALSPYFIALLLFIMVWSVVTELYILRKGGHSLAKQLKARRLVKGESTPEEHAALKITEHLAQTFSLNVPTLYVLPDE---VGVNALTAGFHSNDIVIILTWGALQNLDELELYGLLGHEFNQILSGEAVENTKLKILYSGLTTFSQWGSKLAKQGF---KRYS-PGYKHK--F-----ETVFVAVGGVIWL-AGSLGVLITRFIKYLTLSGRTFRNDQKTMRLLKNSTNAQTLL-RIYVHHSGSQIHSAYSESIAHMCFANSLSPQSWMNIHPSIRERIYELNPTLLQDLQLENLKKLRNRPLFILFHVLEESETEIYTPWSSPQPLPLLRLSPISFALNDAIKPLSSDIRRNKKRPELIQRALQTATGSREVMVAILMIRQYREFIPQDAPVSHAIVDALLNLDGRIHIQIFHDACKNIGHMPASIARQFLTKLALIIQEDGEIGLLDALLLERVKYELNLMPLHLPTAFEEVKPQIVRLIDALLHVQQINSPNQLEVRKRILRSLLNPDEMHIYDEISDEPLDLAEILNDIAGLLLRDRLSILAIVEMCLWSDRIITQDELDVLELLYWRFGFESDEIVEQMQKKNSVMII 4IL3 Chain:B ((229-446)) ----------------------------------------------------------------------------------------------------------DGELKKSIESLADRVGFPLDKIFVIDGSKRSSHSNAYFTGLPFTSKRIVLFDTLVNSNSTDEITAVLAHEIGHWQKNHIVNMVIFSQLHTFLIF-SLFTSIYRNSSFYNTFGFFVEKSSSGFVDPVITKEFP-IIIGFMLFNDLLTPLECAMQFIMSLISRTHEYQADAYAKKLG-YKQNLCRALIDLQIKNLSTM--------NVDPL------YSSYHYSHPTLAERLTALDY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4IL3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 628 -31016 -49.39 -153.54 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain B : 0.52 3D Compatibility (PKB) : -49.39 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.52 QMean score : 0.235

(partial model without unconserved sides chains): PDB file : Tito_4IL3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4IL3-query.scw PDB file : Tito_Scwrl_4IL3.pdb: