Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTDINDYEDAEDSAVDEDEAKAAESGAADEEAGNLTDADLAEA-ETLTVTAKQKQRQALEDEVAAFLARGGRITEVPPDEHSDR 1T11 Chain:A ((114-165)) ----------------EVELKGLENIAVEKPAA---DADVAEMLETL------RKQQATWKEVDEAAENGKRVS----------

General information: TITO was launched using: RESULT: Template: 1T11.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 23 2810 122.15 58.53 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : 122.15 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.474

(partial model without unconserved sides chains): PDB file : Tito_1T11.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1T11-query.scw PDB file : Tito_Scwrl_1T11.pdb: