Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTTLTCFKAYDIRGKLGTELNEEIAYKIGRAYGQIYKPK---TVVVGCDIRLSSEALKQAAIRGLNDAGVNVLDLGMTGTEEVYFAAFHLDVQGGIEVTASHNPMDYNGMKLVRENARPISADTGLKE-IQALAETNNFEEVGQK-GTTQSYNILPEFVDHLLTYIEPAKIRPLKLVVNAGNGAAGHVIDAIEEKFKALNVPVEFIKIHHEADGTFPNGIPNPILIENRDSTRNAVLEHKADMGIAWDGDFDRCFLFDEKGQFIEGYYIVGLLAQAFLIKQSGEKIVHDPRLVWNTFDIVDEYKGVTVQSKSGHAFIKDVMREHNAVYGGEMSAHHYFRD--FAYCDSGMIPWLLTIVLLSETGQSLSTLVENMIAKFP---CSGEINFKVA-DTQTTIQKIFDFYADQNP-QIDRTDGVSLNFGAWRFNVRASNTEPLLRLNIESRADRQAQPMQYYVDELTGLIQN 4MRQ Chain:A ((4-437)) ----SIFRAYDIRGVVGDTLTAETAYWIGRAIGSESLARGEPCVAVGRDGRLSGPELVKQLIQGLVDCGCQVSDVGMVPTPVLYYAANVLEGKSGVMLTGSHNPPDYNGFKIV------VAGETLANEQIQALRERIEKNDLASGVGSVEQVDILPRYFKQIRDDIAMAK--PMKVVVDCGNGVAGVIAPQLIEALGCSVIP-----LYCEVDGNFPNHHPDPGKPENLKDLIAKVKAENADLGLAFDGDGDRVGVVTNTGTIIYPDRLLMLFAKDVVSRNPGADIIFDVKCTRRLIALISGYGGRPVMWKTGHSLIKKKMKETGALLAGEMSGHVFFKERWFGF-DDGIYSAARLLEILSQDQRD----SEHVFSAFPSDISTPEINITVTEDSKFAIIEALQRDAQWGEGNITTLDGVRVDYPKGWGLVRASNTTPVLVLRFEADTEEELERIK------------

General information: TITO was launched using: RESULT: Template: 4MRQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2665 14022 5.26 33.23 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : 5.26 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.479

(partial model without unconserved sides chains): PDB file : Tito_4MRQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4MRQ-query.scw PDB file : Tito_Scwrl_4MRQ.pdb: