Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MCNKASSDLTDYVIRQLGRTKNKRYEAYVVSRIIHLLNDFTLKFVTQQFVRLSNK--KIALTDLYFPQLGIHIEVDEGHHFLRNSKMEYSLNQIDEPLYSISQTESDAMREEDIISITGHKIFRVNVFKNQEGQPQNLENIHQQIDKIIEEIKTAKNKLIEASTFKEWNIETEYNPQTYIDLGRISLADNVVLKTTKDVCNCFGYSYKNYQRGGALHPYK--------KDTLIWFPRLYENKDWINTISPDGLTITEKSTDETITLKKLEEWKNGPQKRIVFARVKDNLSSRAMYRFMGLYEFQKADLKDGA-VWKRVKCEVQTYSPKETKC 4OKY Chain:C ((4-289)) ---------TDYILRALSKISHKRWEHYIINRVVHTLDDPDIEFVCQQCIRKEGHLGKIYLADLLFPQLNLYLEID------NDAR------------------KADAVRRLDIVEATGFQEERI------PASNITLSEVNKLVDEFVRLVKDKKEELENQGLFFRWDYDERYSAKKHINTGYMAVGPNSVFRYHRDALQCFGYRR---QSGGWALPAEVAQSIGLTGRVMVWFPRLYEAGEWKNALSADGNKITEQSLNATRNYQ--ETW----DYRIVMAHSRDEL-NRTLYRFLGVFAIDVDKSSDEVKVFSRVYSRVNVY-------

General information: TITO was launched using: RESULT: Template: 4OKY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1145 22571 19.71 85.17 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain C : 0.76 3D Compatibility (PKB) : 19.71 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.418

(partial model without unconserved sides chains): PDB file : Tito_4OKY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4OKY-query.scw PDB file : Tito_Scwrl_4OKY.pdb: