Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKDIYVEFRGKYKVDGESRDSEHKGWLEVNSWSHNIRQPKSATSSSVGGHTAERVEHSDMVFVKDLDATSPKLWEACSAGYTFDEVQIDFYRANGDKRIKYLQIKLKHVL-VSSVTPTVNEEGVPTEAFGLKYAAVEWTYNQQDINGTAKGAVTK-KWSLSNNTASYAA 1Y12 Chain:A ((12-162)) -------------VKGESKDKTHAE--EIDVLAWSWGMSQSGSMHMGGGG-AGKVNVQDLSFTKYIDKSTPNLMMACSSGKHYPQAKLTIRKAGGENQVEYLIITLKEVLVSSVSTGGSGGEDRLTENVTLNFAQVQVDYQPQKADGAKDGGPVKYGWNIRQNVQA---

General information: TITO was launched using: RESULT: Template: 1Y12.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 573 7470 13.04 50.47 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : 13.04 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.483

(partial model without unconserved sides chains): PDB file : Tito_1Y12.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Y12-query.scw PDB file : Tito_Scwrl_1Y12.pdb: