Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTEELAGEHRLFEKRNCDKTF-----VTVPSFFCYAILDVKNRRNKM-----REIYSFESKIYA----SEVGKGGAYIIFPYD-IRKEFGAGRVKVQATFDNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK 3QMZ Chain:T ((130-212)) ---------KMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGGG----------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3QMZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain T - contact count / total energy / energy per contact / energy per residue : 153 523 3.42 7.68 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain T : 0.65 3D Compatibility (PKB) : 3.42 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.174

(partial model without unconserved sides chains): PDB file : Tito_3QMZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3QMZ-query.scw PDB file : Tito_Scwrl_3QMZ.pdb: