Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQRD--LEKANITI-LPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEV-IRYHDFIGHF-IQNYTSIAVTGSHGKTSTTGLLSHVLSGVR--PTSYL--IGDGTGHGDPQAEF--FSFEACEYRRHFLAYSPDYAIMTNIDFDH-PDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKANVPIYYYGVTEND-DIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVIAVAYFEKL--DLKEVAEEMLTFPGVKRRFS---EKIVADMTVVDDYAHHPAEIKATIDGARQKYPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGAKIKKGGEVIKENNVSPLLD-----YHDAVVIFMGAGDV----QKFEQAYEKLLSSTTKNVL 1J6U Chain:A ((5-446)) ---------FVGIGGIGMSAVALHEFSNGNDVYGSNIEE---TERTAYLRKLGIPIFVPHSADNWYDPDLVIKTPAVRDDNPEIVRARMERVPIENRLHYFRDTLKREKKEEFAVTGTDGKTTTTAMVAHVLKHLRKSPTVFLGGIMDSLEHGNYEKGNGPVVYELDESEEFFSEFSPNYLIITNARGDHLENYGNSLTRYRSAFEKISRNTD-LVVTFAED----ELTSHLGDVTFGVKKGTYTLEMRSASRAEQKAMVEKNGKRYLELKLKVPGF--HNVLNALAVIAL--FDSLGYDLAPVLEALEEFRGVHRRFSIAFHDPETNIYVIDDYAHTPDEIRNLLQTAKEVFENEKIVVIFQPHR--------GNFAKALQLADEVVVTEVYD---------SGKMIWDSLKSLGKEAYFVEKLPELEKVISVSENTVFLFVGAGDIIYSSRRFVERYQSSK--------

General information: TITO was launched using: RESULT: Template: 1J6U.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2242 47886 21.36 120.32 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : 21.36 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.456

(partial model without unconserved sides chains): PDB file : Tito_1J6U.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1J6U-query.scw PDB file : Tito_Scwrl_1J6U.pdb: