Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNNTTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLILAAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPGAGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRNNIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF 1WVI Chain:A ((1002-1254)) -TYKGYLIDLDGTIYKGKDRIPAGEDFVKRLQERQLPYILVTNNTTRTPEMVQEMLATSFNIKTPLETIYTATLATIDYMNDMKRGKTAYVIGETGLKKAVAEAGYREDSENPAYVVVGLDTNLTYEKLTLATLAIQKGAVFIGTNPDLNIPTERGLLPGAGAILFLLEKATRVKPIIIGKPEAVIMNKALDRLGVKRHEAIMVGDNYLTDITAGIKNDIATLLVTTGFTKPEEVPALPIQPDFVLSSLAEWDF

General information: TITO was launched using: RESULT: Template: 1WVI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1433 -172259 -120.21 -680.86 target 2D structure prediction score : 0.76 Monomeric hydrophicity matching model chain A : 0.88 3D Compatibility (PKB) : -120.21 2D Compatibility (Sec. Struct. Predict.) : 0.76 1D Compatibility (Hydrophobicity) : 0.88 QMean score : 0.608

(partial model without unconserved sides chains): PDB file : Tito_1WVI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1WVI-query.scw PDB file : Tito_Scwrl_1WVI.pdb: