Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEKTVSAKIEDLKLDILKQAKVAMEHAVDKEDSAMVAAIAEILAHV 2RR9 Chain:C ((90-120)) --------------KMSEQEAREVNSQEEEEEELLRKAIAESLNS-

General information: TITO was launched using: RESULT: Template: 2RR9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 3 79 26.17 2.53 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain C : 0.64 3D Compatibility (PKB) : 26.17 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.740

(partial model without unconserved sides chains): PDB file : Tito_2RR9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2RR9-query.scw PDB file : Tito_Scwrl_2RR9.pdb: