Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDFNCDLVWMNSMSALLRFTQFVQKTFALWVIIFAALALWQPEFFVWLKAYIPWILGIIMLGMGMTMTVDDFKGVLQSPKAVLIGVVAQFVVMPGLAFILCKLFNLPPEIAVGVILVGCCPGGTASNVITYMAKGNVALSVACTSVSTLLAPVLTPAIFYLLASQWLKIDAASMFISILQVVLLPIVIGLILRTWLKRQVESYIQVMPLVSVIAIVAIVAAIIGGSKAAILQSGLLILAVVILHNGLGYLLGFAAARFFKLPYADSKAIAVEVGMQNSGLGVALAAVHFAASPITAVPSAIFSLWHNISGPALATYWASKHKQE 4N7W Chain:A ((80-108)) ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WILAMLFRMPPDLSAGMVLVGSVASGTAS-------------------------------------------

General information: TITO was launched using: RESULT: Template: 4N7W.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 37 -6892 -186.26 -237.64 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.37 3D Compatibility (PKB) : -186.26 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.37 QMean score : 0.452

(partial model without unconserved sides chains): PDB file : Tito_4N7W.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4N7W-query.scw PDB file : Tito_Scwrl_4N7W.pdb: