Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDEEDIFLITYGDQFFEEQQPTLRTFKKFYQK--YLADT-FRVVHFLPFFPYT-SDDGFSVVNYQAINDRLGTWEDIEEMRSET-----RLMFDFVCNHMSAESTWFQEYLN-LNDTYKDFFIDLPLDTDT---SSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLEKGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKDNISYFGNG---ENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLASHDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSPTDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLLADIEKE--------------------------LQ-TDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSA-DSFISFIREAK---------EEKVLVIHNFSNQSAGYLLPKGDYLDL----FSGQIIH---CSQERKLIFQPYEYMWLKIIK 5JY7 Chain:D ((25-584)) -------------------------------HARTLPTDTNWFKHAVFYEVLVRAFYDSNADGIGDLRGLTEKLDYIKWLGVDCLWLPPFYDSPLRDGGYDIRDFYKVLPEFGTVDDFVTLLDAAHRRGIRIITDLVMNHTSDQHEWFQESRHNPDGPYGDFYVWSDTSDRYPDARIIFVDTEESNWTFD-PVRR--QFYWHRFFSHQPDLNYDNPAVQEAMLDVLRFWLDLGIDGFRLDAVPYLFEREGTNCENLPETHAFLKRCRKAIDDEYPGRVLLAEANQWPADVVAYFGDPDTGGDECHMAFHFPLMPRIFMAVRRESRFPISEILAQTPPIPDTAQWGIFLRNHDELTLEMV----TDEERDYMYAEY---AKDPRMK-----------ANVGIRRRLA---PLLENDRNQIELFTALLLSLPGSPVLYYGDEIGMGDIIWL-----GDRDSVRTPMQWTPDRNAGFSKATPGRLYLPPNQDAVYGYHSVNVEAQLDSSSSLLNWTRNMLAVRSRHDAFAV-GTFRELGGSNPSVLAYIREVTRQQGDGGAKTDAVLCVNNLSRFPQPIELNLQQWAGYIPVEMTGYVEFPSIGQLPYLLTLPGHGFYWFQLRE

General information: TITO was launched using: RESULT: Template: 5JY7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 2763 48018 17.38 96.04 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain D : 0.70 3D Compatibility (PKB) : 17.38 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.409

(partial model without unconserved sides chains): PDB file : Tito_5JY7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5JY7-query.scw PDB file : Tito_Scwrl_5JY7.pdb: