Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence QCNHHLLYNGRHWGTIRKKAGWAVRFYEEKPGQPKRLVTICKNASP--VHCNYLKCTNLAAGFSAGTSTDVLSSG----TVGSIGNDPQAQRQ----- 1HX0 Chain:A ((404-496)) QPFANWWDNGSNQVAFGRGNRGFIVFNND----DWQLSSTLQTGLPGGTYCDVIS-GDKVGNSCTGIKVYVSSDGTAQFSISNSAEDPFIAIHAESKL

General information: TITO was launched using: RESULT: Template: 1HX0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 327 2750 8.41 33.54 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : 8.41 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.236

(partial model without unconserved sides chains): PDB file : Tito_1HX0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1HX0-query.scw PDB file : Tito_Scwrl_1HX0.pdb: