Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKIDILTLFPEMFSPL-EHSIVGKAREKGLLDIQYHNFRE-NAEKARHVDDEPYGGGQGMLLRVQPIFDSFDAIEKKNPR---VILLDPAGKQFDQAYAEDLAQEEELIFICGHYEGYDER-IKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSHQDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLLEHYQLTVEEEKMLAEIKENKE 4YVI Chain:B ((21-261)) MWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGKQASAEEDSFADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQ----

General information: TITO was launched using: RESULT: Template: 4YVI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 973 41133 42.27 175.03 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain B : 0.87 3D Compatibility (PKB) : 42.27 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.87 QMean score : 0.518

(partial model without unconserved sides chains): PDB file : Tito_4YVI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4YVI-query.scw PDB file : Tito_Scwrl_4YVI.pdb: