Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MHPIVIIGSGMAGYTLAREFRKLNPEQELVMICADDAVNYAKPTLSNAFAGKKAPEQIPLGDAAKMSAQLNMRIEPFTWVKEILAERHELVLEKDGIISQQPYSKLILAVGANPIRLAIAGDGSDDIHVVNSLIDYRSFRENLAQRKDKRVVILGAGLIGCEFANDLLHSEYDVTVIDLAPQPLGRLLPSHIASAFQQNLEEAGVKFTLGTTVEKVSKINNGEDYAVTLANGQTLVADIVLSAIGLQPNISLAQSANIQT--SRGVITNSLLETNQADIYAIGDCAEVNGTL------LPYVMPIMQQARALAKTLSGQQTNVHYPAMPVAVKTPAAPLTVLPAPVDVDVNW-------ETE-----EFDDGM-LAKAIDNEGTLRGFVLLGATAGKQRLTLTKLVPDLIPAQA 3OC4 Chain:B ((2-404)) SLKIVIIGASFAGISAAIASRKKYPQAEISLIDKQATVGYLSG--------------AR-YITEEELRRQKIQLLLNREVVAMDVENQLIAWTRKEEQQWYSYDKLILATGASQFSTQIRGSQTEKLLKYKF------AVPLLEN--SQTVAVIGAGPIGMEAIDFLVKMKKTVHVFESLENLLPKYFDKEMVAEVQKSLEKQAVIFHFEETVLGIEET-A-NGIVLE-TSEQEISCDSGIFALNLHPQLAYLDK-KIQRNLDQTIAVDAYLQTSVPNVFAIGDCISVMNEPVAETFYAPLVNNAVRTGLVVANNLEEKTHRFIGSLRTMGTKVGDYYLASTGLTETEGLFFPQTLASIIVRQPAPPHGTEILGKLIYDKVTQRVLGAQLCSKNNCLEKINTLALSI-------

General information: TITO was launched using: RESULT: Template: 3OC4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1989 -172099 -86.53 -479.38 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain B : 0.67 3D Compatibility (PKB) : -86.53 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.464

(partial model without unconserved sides chains): PDB file : Tito_3OC4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3OC4-query.scw PDB file : Tito_Scwrl_3OC4.pdb: