Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELDVKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMINYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQA-PPSSIEWLPTETDDFVAVLPKNHPLAS--KKKLDLSELKKENFLLLGPTT--NLYQPVLDLCREAGFEPKISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPT---TESYLAFTRKVGEHSLASDTFWEYLNQEEN 2H98 Chain:A ((89-292)) ------------------------------------------------------------------------------------------SQTLRIGYVSSLLYGLLPEIIYLFRQQNPEIHIELIECGTKDQINALKQG---KIDLGFGRLKITDPAIRRIMLHKEQLKLAIHKHHHLNQFAATGVHLSQIIDEPMLLYPVSQKPNFATFIQSLFTELGLVPSKLTEIREIQLALGLVAAGEGVCIVPASAMDIG-VKNLLYIPILDDDAYSPISLAV-RNMD-HSNYIPKILACVQEV--

General information: TITO was launched using: RESULT: Template: 2H98.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 997 -11906 -11.94 -60.74 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -11.94 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.456

(partial model without unconserved sides chains): PDB file : Tito_2H98.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2H98-query.scw PDB file : Tito_Scwrl_2H98.pdb: