Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ------MNFNIAKVMSIDQLETQIAELDNLPEHREIVTFMRRSAPLNTSQRTALEQHRDLILEYPVGDLRQHFEHPERPLTVEIGFGMGRSLVLMAKA-NPERNYVGIEVHVPGIAQCVYEAGMAELKN-LRVLDADAIQILREMPDN-SINCVQLYFPDPWQKKRHFKRRFVIHERMQLVEQKLELGGTFHAATDWEPYAEWMLDVLDNRPNLENLAGKGNSYPRPEWRPVTKFERRGIESGHKINDFIFKKIK 5FHR Chain:A ((1-213)) DTKEQRILRYVQQNAKPGDPQSVLEAIDTYCTQKE--------WAMNVGDAKGQIMDAVIREYSP-------------SLVLELGAYCGYSAVRMARLLQPGARLLTMEMNPDYAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDMVFLD------HWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFE----CTHYSSYLELMKVVDGLEKAIYQGP-----------

General information: TITO was launched using: RESULT: Template: 5FHR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1018 -1296 -1.27 -6.35 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -1.27 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.385

(partial model without unconserved sides chains): PDB file : Tito_5FHR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5FHR-query.scw PDB file : Tito_Scwrl_5FHR.pdb: