Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ------------------------------------------------------------------------MYNRSVMINLNVRSEMALQILQ------KQLDESSHCPLCQA-SMYWVDAEQ---FEQDVQFHECSHCQHRVFKDTKMTCHCDQCTKQRKKLLQQTRLQEQRQFKLKDQPQRSLEQLSFLHKLFLLSLLDDYARDDVAHDEYIHWDQIKYQPITPNWMFQSH----------------------LIKQLHKDGILNAQDQTDEPQCFYLNIRLDGYSDPSLFSVAQQLRH------------WFYENLSLGI-PFRS----ADEVKDV--------------LFQVLYQEI-IQFTQFYCRTWGIQIAGSSN--FQA-FCYRLMD-SLAIGQI-YYLIQTAL---------EYLYKQKALQPRNEKFINTNLLK-KTLEQYRE-RALAEKWETSMLPRPYNIPYSKMSHILFNRFLGY----DEQIFVQPVWKAWRKI-EPRLNFYSV--KRCMYCGSNDLSVDYDAADYVSLICQNCKHQDHYFTR---------------------------------- 4YCZ Chain:B ((314-1176)) SEYRYAALAKDAYQQMGTAPVTEPPQVILGTEDLLSRLYDEKMDDTLATAAAQLAALWREHVDETPFEKANYLANLALQIHHPLPQTLFRWLNEYHMYGSQVDDILRHRPSPACHSLFWQAVFIALKVGDAARLLDQAGWGH-VYAYVNVQRAVDETIAVLESCPTLFRVRARGLLEHLRRFAEGWEIYENLNIVFDIVLGQQGAILEAAQDWLEATVGLANSESYLDRLARAFHTAVESDFVEIGMACVFEDNIKGVIGLLRGWSLPIAAAVAEIASLGKWLEVDGIKDSTLVQYAQALADYEGLSSVQDRDGWELSISVLGRMPERSEEMVRDLVEHLVQQLHVDSNATVDRLWFLLNELGMIEFAEDTTETYGDILARDSHRYGEAMWYYALAHRPNKVREVMNLLTSYSLIQPPANDLDDYLYK--LLNDRKNTLEQCASQDMEAAELLGKMLSGYASLRQFYDIRPHATPLSRRKQAATALISVIASSDDEDFLLALLGEALVFVSDPTLDQIDVLLKAIEDLQAVGSRVYNACDEFLQLVLASAPGGSSLVASQLQRSLSGTGGEDIMRRLRLGLAKDLAGLWLAEA

General information: TITO was launched using: RESULT: Template: 4YCZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1586 -16909 -10.66 -42.59 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain B : 0.62 3D Compatibility (PKB) : -10.66 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.087

(partial model without unconserved sides chains): PDB file : Tito_4YCZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4YCZ-query.scw PDB file : Tito_Scwrl_4YCZ.pdb: