Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTEIIQPNEEIRITDGSKVDLHFSVAIENGVEIDNTRSR-------------EEPVSLTIGDGNLLPGFEKALLGLRAGDRRTVHLPPEDAFGPWNPENIQTFDTVKFEQR---PIPGHMIEFEDKAKATLFGVVKSVNDDITEIDFNHPLAGKNITFEVEIFKVTPAGQQGIKIM 3PR9 Chain:A ((2-150)) ------------VEKGKMVKISYDGYV-DGKLFDTTNEELAKKEGIYNPAMIYGPVAIFAGEGQVLPGLDEAILEMDVGEEREVVLPPEKAFGKRDPSKIKLIPLSEFTKRGIKPIKGLTITID---G--IPGKIVSINSGRVLVDFNHELAGKEVKYRIKIEEVVD---------

General information: TITO was launched using: RESULT: Template: 3PR9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 446 18079 40.54 135.93 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : 40.54 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.643

(partial model without unconserved sides chains): PDB file : Tito_3PR9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3PR9-query.scw PDB file : Tito_Scwrl_3PR9.pdb: