Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMNILHVAPE--Y---KWSKIFILPIANCQIQQGNKVWISAPNVLENTSELD-EAKFVSWNSKYKN---IF------KHIG-RLFLILK--MVHKYKINKVYFHTTVDSTLNIFILSLFSSAQLVYVNHGVPYLGYSS-IMQYILKLCEIVNINFSHRSITITQSMKQLLEPLNYKKKEITALIPGTLVGVKIPYSSYTDL-QSARALLKTNSDNSILKILYVGRLEHRKGIYDLIEAINHTNL-----NCELTVLGGTANELET-----E-LDLLKVKFEGFQ--SDLRSYYLNADLLCVPSHHEGFGQVYLEAAAHGVIPVCCNIPGPTDLIKHNSNGFIVEAKSPDSILELFEEINLKKFDLDAIQKRAFESVQAYESSQVISNNMDHF 3C48 Chain:B ((21-422)) -MRVAMISMHTSPLQQ-GMNVYILSTATELAKQGIEVDIYTRATRPSQGEIVRVAENLRVINIAAGPYEGLSKEELPTQLAAFTGGMLSFTRREKVTYDLIHSHYWL-SGQVGWLLRDLWRIPLIHTAHTLAAVK---TPESEARRICEQQLVDNADVLAVNTQEEMQDLMHHYDADPDRISVVS---PGADVELYSPGNDRATERSRRELGIPLHTKVVAFVGRLQPFKGPQVLIKAVAALFDRDPDRNLRVIICGGPS---TYRHMAEELGVEKRIRFLDPRPPSELVAVYRAADIVAVPSFNESFGLVAMEAQASGTPVIAARVGGLPIAVAEGETGLLVDGHSPHAWADALATLLDDDETRIRMGEDAVEHARTFSWAATAAQLSSLY

General information: TITO was launched using: RESULT: Template: 3C48.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1843 -20155 -10.94 -58.08 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain B : 0.66 3D Compatibility (PKB) : -10.94 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.364

(partial model without unconserved sides chains): PDB file : Tito_3C48.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3C48-query.scw PDB file : Tito_Scwrl_3C48.pdb: