Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSIRVETQMYKSYLFGSKSLLLISLSMLPMFVSAKTILILGDSISAGYGIDPKQGWVQLLQKRLDQQYPKQHKVVNASVSGETTSGALARLPKLLQTYKPEVVVIELGGNDGLRGQPPQMIQQNLSQLIQLSQKQKAKVILFGMKIPPNYGTAYSKAFENNYKTVSQKYQVKLLPFFLDGVAGQKQLMQNDLIHPNAQAQSKLLNLAYPYIKGAL- 1IVN Chain:A ((1-179)) ---------------------------------ADTLLILGDSLSAGYRMSASAAWPALLNDKW-----SKTSVVNASISGDTSQQGLARLPALLKQHQPRWVLVELGGNDGLRGFQPQQTEQTLRQILQDVKAANAEPLLMQIRLPANYGRRYNEAFSAIYPKLAKEFDVPLLPFFMEEVYLKPQWMQDDGIHPNRDAQPFIADWMAKQLQPLVN

General information: TITO was launched using: RESULT: Template: 1IVN.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 893 -96525 -108.09 -545.34 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -108.09 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.601

(partial model without unconserved sides chains): PDB file : Tito_1IVN.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1IVN-query.scw PDB file : Tito_Scwrl_1IVN.pdb: