Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence TQKCIITIRKADPALGQDTLYDLVSLAPNSDLTFGKIPASMTEVTFGVDEKCQA----RLVRGDLSRPYEYKGMQNPLYGLDGPDFVKKLQAWRRKPENSINFSLW-- 1IU0 Chain:A ((1-91)) MEYEEITLERGNSGLG-------FSIAGGTDNPHIGDDPSI--FITKIIPGGAAAQDGRLRVND--SILFVNEV--DVREVTHSAAVEALK----EAGSIVRLYVMRR

General information: TITO was launched using: RESULT: Template: 1IU0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 410 -12787 -31.19 -150.43 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -31.19 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.274

(partial model without unconserved sides chains): PDB file : Tito_1IU0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1IU0-query.scw PDB file : Tito_Scwrl_1IU0.pdb: