Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---MKDSIVEPEGMENTFELYNKTTVDKLIPILVPTDLNGHDVLLRFNGFLGEDYRYLKISDPQPLTE-- 5JRT Chain:A ((11-74)) VDFSITQFVRNLGLEHLMDIFEREQIT--LRVLVEM---GHKELKEI-GINAYGHREKLIKGVERLISGQ

General information: TITO was launched using: RESULT: Template: 5JRT.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 191 3961 20.74 67.14 target 2D structure prediction score : 0.32 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : 20.74 2D Compatibility (Sec. Struct. Predict.) : 0.32 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.108

(partial model without unconserved sides chains): PDB file : Tito_5JRT.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5JRT-query.scw PDB file : Tito_Scwrl_5JRT.pdb: