Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYKLDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKV---DDIEETIAELQSLGIESEPIREDTFT---GKKMTFFFDPDGLPLELHE 4Z6Z Chain:C ((23-128)) ----------LVVTDLAKSRNFYVDVLGLHV---SYEDENQIY-----LRSFEEFIHHNLVLTKGP----VAALKAMAFRVRTPEDVDKAEAYYQELGCRTER-RKDGFVKGIGDALR-VEDPLGFPYEF--

General information: TITO was launched using: RESULT: Template: 4Z6Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 331 -9139 -27.61 -91.39 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain C : 0.75 3D Compatibility (PKB) : -27.61 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.369

(partial model without unconserved sides chains): PDB file : Tito_4Z6Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4Z6Z-query.scw PDB file : Tito_Scwrl_4Z6Z.pdb: