Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRGVNKVILVGTLGRDPETKTFPNGGSLTQFSIATSEVWTDKNTGERKEQTEWHRIVLHNRLGEIAQQFLRKGSKVYIEGSLRTRQWTDQNGQERYTTEIRGDQMQMLDARQQGEQGFAGGNDFNQPRFNAPQQGGGYQNNNQGGGYGQNNGGYDGQGGFGNGGNSPQGGGFAPKAPQQPASAPADLDDDLPF 2VW9 Chain:A ((1-108)) --MFNKVIMVGRLTRNVELKYLPSGSAAATIGLATSRRFKKQ-DGTLGEEVCFIDARLFGRTAEIANQYLSKGSSVLIEGRLTYESWMDQTGKKNSRHTITADSLQFMDKK----------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2VW9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 421 -33378 -79.28 -309.06 target 2D structure prediction score : 0.46 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -79.28 2D Compatibility (Sec. Struct. Predict.) : 0.46 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.683

(partial model without unconserved sides chains): PDB file : Tito_2VW9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2VW9-query.scw PDB file : Tito_Scwrl_2VW9.pdb: