Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MITTSVTEAAECLQQGQVLAYPTEAVWGLGCDPFNEQAFQKILELKQRPIEKGVILLAGHISQVEHLLTSLPQTTQQEIIDCWTNHQPSERATTWLLPADQ-HIPSWIKGEHPLVAVRVTTHPLCVALCNAFHGFIVSTSANPSGQEPAHSLQDACQYFGS-QLNYLNGDL-GQSQQPSRIINALTGEVIRP 3TTC Chain:A ((111-284)) --EAALQAAIAQLKMGNIVAIKGIGGFHLACDARNSNAVATLRARKHRP-AKPLAVMLPVADGLP-------DAARQLLTT-PAA------PIVLVDKKYVPELCDDIAPGLNEVGVMLPANPLQHLLLQELQCPLVMTSGNLSGKPPAISNEQALEDLQGIADGFLIHNRDIVQRMDDSVVRESG-EMLRR

General information: TITO was launched using: RESULT: Template: 3TTC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 855 -56019 -65.52 -327.60 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -65.52 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.448

(partial model without unconserved sides chains): PDB file : Tito_3TTC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3TTC-query.scw PDB file : Tito_Scwrl_3TTC.pdb: