Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTSSYRQQLQAKIDRITTQFSEFTPPTLEVFESPEQHFRMRAEFRIWHTENDMFYAMFERNDDGKQKTVVRIDE---FPIADKSINDLMPLLLAELKANSLLSQRLF--EVD----FLATLSGEMLVTLIYHRKLNQEWEQAAKALAEKLN----IKIMGRSRGQKIVIGDDFVVEEFELLNRSFKYKQIESSFTQPNAQVCKKMLQWACDAAEGSKKHLLELYCGNGNFTLPLSLK-FERVLATELAKSSVYAAQWNIEQNQIDNIQVARLSAEEFTQAYQGEREFRRLQEADIDIQSYDFGTVFVDPPRAGIDDETLKLLQGFERIIYISC----NPDTLYENLKTLTQTHRVTKFALFDQ---FPYTHHVESGVLLEKI---- 2B78 Chain:A ((1-385)) MIKLMVG--SFAEKKLKRGVQLLSSRDYPNLNLDNQVVQLYSD-----ADIFLGTAYLSKQNKGVGWLISPKKVSLNVTYFIKLFQWSKDKRKNFAHSKLTTAYRLFNQDGDSFGGVTIDCYGDFVLFSWYNSFVYQIRDEIVAAFRQVYPNFLGAYEKIRFNVSAHLYGQE-APEQFLILENGISYNVFLNDGLMTGIFLDQRQVRNELINGSAAGKTVLNLFSYTAAFSVAAAMGGAMATTSVDLAKRSRALSLAHFEANHLDMANHQLVVMDVFDYFKYARRHHLTYDIIIIDPPSFEVFS--VSKDYHKLIRQGLEILSENGLIIASTNAANMTVSQFKKQIEKGFGKQKHTYLDLQQLPSDFAVNVQDESSNYLKVFTIKV

General information: TITO was launched using: RESULT: Template: 2B78.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1853 -12252 -6.61 -34.90 target 2D structure prediction score : 0.48 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -6.61 2D Compatibility (Sec. Struct. Predict.) : 0.48 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.167

(partial model without unconserved sides chains): PDB file : Tito_2B78.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2B78-query.scw PDB file : Tito_Scwrl_2B78.pdb: