Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDVFDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESL-PGQFDQRAASSQEALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFSESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVLDTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMATIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPFGGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGYSSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAG---DVIILLGGK-TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDFGAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVAECNKENIDAVVVATVTEK------PNLVMHWNGETIVDLERRFLDINGVRVVVDAKVVDKDVKLPEERQTSAETLESDTLTVLS-DLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEASVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARFSYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLVAFGVTTADSR--KVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVTSASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVE----KIGQTKADFTLTVNGVKL--DGHKLDSAFQGTLEEVYPTEF-TQAKELEEVPAVASDVVIKAKEKVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDKTNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVKSGLLPYGNFEDANNTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVSHGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQIIGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK 5IJL Chain:A ((9-1044)) PKEMEEYFEMLQREIDKAYEIAKKARAQ-GKDPSLDVEIPQATDMAGRVESLVGPP--------GVAKRIRELVKEYGKEIAALKIVDEIIEGKFG------------------------------------DLGSREKYAEQAVRTALAILTEGIV----SAPIEGIANVKIKRNTWA----------------DNSEYLALYYAGPIRSS-GGTAQALSVLVGDYVRRKLGLDRFKPSEKHIERMVEEVDLYHRAVTRLQYHPS-PEEVRLAMRNIPI----EITGEATDDVEVSHR----------DVPGVETNQLR----------------GGAILVLAEGVLQKAKKLVKYIDKMGIEGWEWLKEFVEAKEKGV---------------DMGFYYSLYQKFKEEPLFSD------------PSKPGGFRLRYGRSWGINPATMILVGAVVTPVTTIEGPIVKLKDGSVLRVDD----YNLALKVREDVEEILYLGDAVIAFGDQTLLPANYCEEWWILEFVKALK-EIYEVHLEPFTEN-EEESIEEASDYLEI--DPEFLKEMLRDPLRVKPPVELAIHFSEVLGIPLHPYYTLYWNSVEPKDVEKLWRLLKNYAEIEWSNF--RGIKFAKKIVISQEKLGDSKRTLELLGLPHTVRDG-NVIVDYPWAAALLT-PLGNL-----------------------------------NWEFMAKPLYATIDIINEN-----NEIKLR----------DRGISWIGKPPVQVL------FPIGLAGGSSRDIKKAAEEGKVAEVEIAFFKCPKCGHVGPEHLCPNCGTRKELLWVCP-----------------------RCNAEYPESQAEGYNYTCPKCNV-KLRPYAKRKIRPSELLNRAMENVKVYGVDKLKGVMGMTSGWKMPEPLEKGLLRAKNDVYVFKDGTIRFDATDAPITHFRPREIGVSVEKLRELG-------------------YTHDFEG--------KPLVSEDQIVELKPQDIILSKEAGRYLLKVAKFVDDLLEKFY--GLPRFYNAEKMEDLIGHLVIGLAPHTS--------AGIVGRIIGFVDALVGYAHPY--FHAAKRRNC-----DGDEDAVMLLLDALLNFSRYYLPEKRGGKMDAP--------LVITT-----------------------RLDPRY----------------------------YPLEFYEATYELKSPKELVGVIERVED-

General information: TITO was launched using: RESULT: Template: 5IJL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 5337 157355 29.48 170.67 target 2D structure prediction score : 0.49 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : 29.48 2D Compatibility (Sec. Struct. Predict.) : 0.49 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.212

(partial model without unconserved sides chains): PDB file : Tito_5IJL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5IJL-query.scw PDB file : Tito_Scwrl_5IJL.pdb: