Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLI--ANIKESTLYPILKKLEGNSFLTTYSRE-FQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGSIRHDKN 3HHH Chain:B ((8-107)) ---ELLKGILEGLVLAIIQRKETYGYEITKILNDQGFTEIVEGTVYTILLRLEKNQWVIAEKKPSEKGPMRKFYRLTSSGEAELADFWQRWTLLSKQVNKMKK--------

General information: TITO was launched using: RESULT: Template: 3HHH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 305 2129 6.98 21.95 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain B : 0.77 3D Compatibility (PKB) : 6.98 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.502

(partial model without unconserved sides chains): PDB file : Tito_3HHH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3HHH-query.scw PDB file : Tito_Scwrl_3HHH.pdb: