Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLD-EYFTMMAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI 1U8S Chain:B ((94-180)) --VEVYVESDDKLGLTEKFTQFFAQRQIGMASLSAQTISKNQFHIAISARVDSGCNLMQLQEEFDALCTALDVQGSLNFIKN-------

General information: TITO was launched using: RESULT: Template: 1U8S.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 293 -15510 -52.94 -196.33 target 2D structure prediction score : 0.46 Monomeric hydrophicity matching model chain B : 0.68 3D Compatibility (PKB) : -52.94 2D Compatibility (Sec. Struct. Predict.) : 0.46 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.495

(partial model without unconserved sides chains): PDB file : Tito_1U8S.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1U8S-query.scw PDB file : Tito_Scwrl_1U8S.pdb: