Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNFNHVYFGYDENRP---VLKDITCSIFKGQKIAFVGPSGSGKSTIVRLLEQFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRLLSGGAKPKTSNS 2IXF Chain:C ((17-162)) VKFQDVSFAYP-NHPNVQVLQGLTFTLYPGKVTALVGPNGSGKSTVAALLQNLYQPTGGKVLLDGEPLVQYDHHYLHTQVAAVGQEPLLFGRSFRENIAYGLTRTPTMEEITAVAMESGAHDFISGFPQGYDTEVGETGNQLSGGQR------

General information: TITO was launched using: RESULT: Template: 2IXF.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 457 9239 20.22 64.61 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain C : 0.83 3D Compatibility (PKB) : 20.22 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.496

(partial model without unconserved sides chains): PDB file : Tito_2IXF.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2IXF-query.scw PDB file : Tito_Scwrl_2IXF.pdb: