Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEEMSMRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPFSTFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLFGIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFLTRTVRLQ 1DD3 Chain:A ((1-128)) ---MTIDEIIEAIEKLT----VSELAELVKKLEDKFGVTAAAPVAVAAAPVAGAAAGAAQEEKTEFDVVLKSFG------------QNKIQVIKVVREIT-------GLGLKEAKDLVEKAGS------PDAVIKSGVSKEEAEEIKKKLEE------------AGAEVELK

General information: TITO was launched using: RESULT: Template: 1DD3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 445 -72479 -162.87 -566.24 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.58 3D Compatibility (PKB) : -162.87 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.58 QMean score : 0.238

(partial model without unconserved sides chains): PDB file : Tito_1DD3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1DD3-query.scw PDB file : Tito_Scwrl_1DD3.pdb: