Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLYCIFLTYLIKYAIIISEKGGETMANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIGLEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL 2ODK Chain:D ((2-51)) -------------------------HMHVWPVQDAKARFSEFLDACIT-EGPQIVSRR-GAEEAVLVPIGEWRRLQA----------------------------------

General information: TITO was launched using: RESULT: Template: 2ODK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 148 -9134 -61.71 -182.67 target 2D structure prediction score : 0.82 Monomeric hydrophicity matching model chain D : 0.60 3D Compatibility (PKB) : -61.71 2D Compatibility (Sec. Struct. Predict.) : 0.82 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.598

(partial model without unconserved sides chains): PDB file : Tito_2ODK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2ODK-query.scw PDB file : Tito_Scwrl_2ODK.pdb: