Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ------MTITPKPDSVVYRVRVAVPVHLYDTFDYTLTKAQYERAQVGSRVAISFGRQNLIGIITEKVDPQESFTGNFQLKAISELLDDEPILD---EQVLNLLTW-SAQYYQFPIGEVMQTALPALLRQGKP-MD------VLFHLWKII--PCDNAEALLKRSIKQQD----------------------------------AYQILKLH--PAGTTENILNLS-----------------------------GVETATLKALQKKGLVDCT-LE--------PHDFSPAPV-QLAQM-----------------------PLTLNEDQ----------------------------------------KKATQHVLNAQHQYQAFLLD---------------GL----TGSGKTEVYLHIMHEVL--KQGKQVLVLVPEIGLTPQTISRFKSRFNC---DIALL-----HSGLNDSKRLQ-----------AWQQAQTGKASIILGTRSAI-----------------YTPLPRL--GLIILDEEHDLSYKQQEGFRYHARDVALYRGHLQGCPVLLGSAT--PSIDS--YHLVETGKLTALQLNQRAGHALLPKMHLID-LKIVKKQHGISQPLIEQIKNTLARKEQVLIFLNRRGYAPVLVCESCGWQANCPHCDAHFTLH-TQP-YSYLHCHHCGT--------VHRLP--DHCPECQQKSLKTLGAGTAKVEEHLQELFPDHDVIRVDRDSTSRVGSWQKIYDRIQQNKPSILLGTQM---LAKGHHFPHVTLVAILDI-DAGL-LSVDIRAPERTA-QLIVQVAGRAGR------GEHKGHVYLQTLR----------------PDHPLLTTLIEK--DYRAVAKQTLAERKVALLPPYRYAVLIRAESKD-RDY-TLHFLNEAAEQLRQIAGGIVDIWGPIPAPMERKAGRYRAHMVIL--SADRTRLHFYLRQ-----------------------------WWAQLVH-APRQH-QLRLSI----DVDPQEFS--------------- 5B7I Chain:A ((4-1082)) SEFMNILLVSQCEKRALSETRRILDQFAERRGERTWQTPITQAGLDTLRRLLKKSARRNTAVACHWIRGRDHSELLWIVGDASRFNAQGAVNDWHSAEDIRLLTVMAALFHD--IGKASQAFQAKLRNRGKPMADAYRHEWVSLRLFEAFVGPGSSDEDWLRRLADKRETGDAWLSQLARDDRQSAPPGPFQKSRLPPLAQAVGWLIVSHHRLPNGDHRGSASLARLPAPIQSQWCGARDADAKEKAACWQFPHGLPFASAHWRARTALCAQSMLERPGLLARGPALLHDSYVMHVSRLILMLADHHYSSLPADSRLGDPNFPLHANTDRDSGKLKQRLDEHLLGVALHSRKLAGTLPRLERQLPRLARHKGFTRRVEQPRFRWQDKAYDCAMACREQAMEHGFFGLNLASTGCGKTLANGRILYALADPQRGARFSIALGLRSLTLQTGQAYRERLGLGDDDLAILVGGSAQELLAENSHVHFAGTLEDGPLREWLGGNSAGNRLLQAPILACTIDHLMPASESLRGGHQIAPLLRLMTSDLVLDEVDDFDIDDLPALSRLVHWAGLF-----GSRVLLSSATLPPALVQGLFEAYRSGREIFQRHRGAPGRATEIRCAWFDEFSSQSSAHGAVTSFSEAHATFVAQRLAKLEQLPPRRQAQLCTVHAAG--EARPALCRELAGQMNTWMADLHRCHHTEHQGRRISFGLLRLANIEPLIELAQAILAQ--GAPEGLHVHLCVYHSRH--PLLVRSAIER--QLDELLKRSDDDAAALFARPTLAKALQASTERDHLFVVLASPVAEVGRDHDYDWAIVEPSSMRSIIQLAGRIRRHRSGFSGEANLYLLSRNIRSLEGQNPAFQRPGFETPDFPLDSHDLHDLLDPALLARIDASPRIVEPFPLFPRSRLVDLEHRRLRALMLADDPPSSLLGVPLWWQTPASLSGALQTSQPFRAGAKERCYALLPDEDDEERLHFSRYEEGTWSNQDNLLRNLDLTYGPRIQTWGTVNYREELVAMAGREDLDLRQCAMRYGEVRLRENTQGWSYHPYLGFKKYN

General information: TITO was launched using: RESULT: Template: 5B7I.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 3879 68565 17.68 94.31 target 2D structure prediction score : 0.48 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : 17.68 2D Compatibility (Sec. Struct. Predict.) : 0.48 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.230

(partial model without unconserved sides chains): PDB file : Tito_5B7I.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5B7I-query.scw PDB file : Tito_Scwrl_5B7I.pdb: