Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTQYFFLFPKIDQKKNGLVFALLKRAKILNEQLGISPTIITTEYDRSLAENYWSLIATNLAPPSIGYLNLYADFQGTHLKLANKKIHDPAIEMFNSNILKTII----PFTYNQRFHDKNNKNYLYEIRQNDSITLRYVNTFKK-GVKTGRIIYDSYGYLSCIQVINPENQMIITETYYHTEGYPVIIKNYQLNEKNKNIVSNIFLFNKQGVINEVFETESQLIQYWFLKISQLYENDLMYILI-DRAIHFYEPLREI--KQENMRFIGTIHATHLNGHDIQNSTINRHYRSYFKYSNELDALVILTERQKQHIQQRFGMEEKLFVIPHIYEKTIDHVNFSNRDPMFCLTIARYDKAKNLDSLIRIFKKVVEVIPNAYLNIYGFGSEHNFLQSQIDEHQLNNHIKLMGYNENTDALYNKASLFLFSSRSEGFGMAVLEALCHGCPVVSYDIDYGPSDMIKHDENGYLVTFQDEESFAQKVVSLLKDEHKRLKLSENAYACI-QLTDQKQFALKWQELFQAIQ 4X7M Chain:B ((1-492)) -MKKIFMMVHELDVNKGGMTSSMFNRSKEFYD-ADIPADIVTFDYKGNYDEIIKALKKQGKMDRRTKMYNVFEYFKQISNNKHFKSNKLL---YKHISERLKNTIEIEESKGISRYFD--ITTRTYIAYIRKSKSEKVIDFFKDNKRIERFSFID--NKVHMKETFNVDNK-VCYQVFYDEKGYPYISRNINANNGA--VGKTYVLV-----NKKEFKNNLALCVYYLEKLIK--DSKD-SIMICDGPGSFPKMFNTNHKNAQKYGVIHVNHHENFDDTG----AFKKSEKYIIENANKINGVIVLTEAQRLDILNQFD-VENIFTISNFVKIHNAP--KHFQTEKIVGHISRMVPTKRIDLLIEVAELVVKKDNAVKFHIYGEGSVKDKIAKMIEDKNLERNVFLKGYTTTPQKCLEDFKLVVSTSQYEGQGLSMIEAMISKRPVVAFDIKYGPSDFIEDNKNGYLIENHNINDMADKILQLVNNDVLAAEFGSKARENIIEKYSTESILEKWLNLFN---

General information: TITO was launched using: RESULT: Template: 4X7M.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2556 80954 31.67 167.61 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain B : 0.70 3D Compatibility (PKB) : 31.67 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.489

(partial model without unconserved sides chains): PDB file : Tito_4X7M.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4X7M-query.scw PDB file : Tito_Scwrl_4X7M.pdb: